Filling station premises on the Dobbin Road near Portadown were ransacked during the early hours of Tuesday morning.
Some time between midnight and 7am on Tuesday, July 29 an external alarm was ripped from an outside wall and entry was forced through the roof. Cigarettes were taken and the premises were ransacked.
It is believed a vehicle would have been needed to transport the cigarettes.
Police are appealing to anyone who noticed any vehicles or people around the filling station during this time to contact them in Portadown on the 101 non-emergency number, quoting ref: 74290714. If you prefer to provide information without giving your details you can contact the independent crimestoppers charity anonymously on 0800 555 111.